Zeolites and Mesothelioma Cancer

Mesothelioma and asbestos exposure has long been linked hubungkankan. Since the early days of the Holy Roman Empire had noted that slaves who worked in asbestos mines have lung problems are severe and died at an early age. However, in recent decades it has become apparent that there are other potential causes for the development of a rare form of cancer.
A study conducted by McDonald and McDonald in 1980 showed that About a 25-33 percent of all cases of mesothelioma cancer does not have anything to do with exposure to asbestos. However, in research prefix found some other specific cause. One of them is the exposure of the zeolite.
Zeolite (wikipedia.org)Is the zeolite?
Known in scientific terms as alkali hydrated aluminum silicate. Zeolite is a mineral group that contains most of hydrated aluminum and silicon compounds. Their common names include clinoptilolite, erionite, Phillipsite, and Mordenite. They are found in volcanic rock and ash and is sometimes used as an additive in animal feed. Because of their porous structure, zeolites can be used as an absorbent (absorbent materials), textile printing materials, detergents, and as purifying water and air.
Zeolites have also been used in several areas of health, among others as a supplement to a hangover and an adjuvant therapy for various cancers (FDA did not approve of this treatment). But there is still a lack of data supporting the efficacy of the effectiveness of zeolite and no conclusion as to whether zeolite secure. As a mineral that has a systemic effect on the body, zeolite also remains unclear to this day and requires further research.
Zeolite relationship with mesothelioma
It has become clear, however, that zeolite dust exposure is associated with an increased risk of development of malignant mesothelioma (malignant mesothelioma). Simply to say zeolites are carcinogenic when inhaled. As a matter of International Agency for Research on Cancer placing the zeolite in the list of groups 1. Categorization inidiberikan carcinogens when there is sufficient evidence regarding carcinogenicity in humans causes mesothelioma.Erionite zeolite is a form of fiber that is clearly associated with mesothelioma epidemic in villages Anatolian Plateau in Turkey. In the village local volcanic tuff filled with zeolite toxic fibers. A report on the epidemic published in the 2006 edition of March 15 Journal of the National Cancer Institute.
Doctors in Turkey initiated a study during the 23 years that followed 891 men and women living in three villages in different Turkish Cappadocia region. Villagers had been exposed to erionite. The third village used as a village controlled. During the study which started from 1979 to 2003 as many as 372 people have died. Of the deaths are known to many as 119 people stricken with mesothelioma cancer and died from the disease or complications of the disease. In the two villages where the population is exposed to the toxic mineral known deaths from pleural mesothelioma amounted to 44.5 percent. While in the third village just happened two deaths caused by mesothelioma, and even then it is known that the two of them when they are born not from the village controlled.
Data analysts, including from Harvard professors, namely Philippe Grandjean, MD, Ph.D., determines the result of mesothelioma in the two events. The village is filled with erionite occurs 200-700 cases per 100,000 people annually. In the village there are only controlled 10 cases per 100,000 people. Therefore, the conclusion is that long-term exposure to erionite is responsible for a very high incidence of the cancer cases of asbestos in certain villages of Cappadocia in the Anatolian Plateau.
After the study is completed, the authors suggest that local authorities were concentrating on ways to prevent exposure to the environment from harmful zeolite fibers in the hopes of lowering the risk population for developing the disease mesothelioma.
The precipitate natural erionite have been found in several western US states, especially Arizona, Nevada, Utah, Oregon, North Dakota, South Dakota, and Montana. A report on ereonite / zeolite in the US (Rom, WN, KR Casey, WT Parry, CH Mjaatvedt and F. Moatamed. 1983. Health implications of natural fibrous zeolites for the Intermountain West. Environ Res 30 (1): 1- 8) noted that residents of the area known as the "Intermountain West" may be exposed to fibrous zeolite from wind gusts and therefore vulnerable to the development of mesothelioma. The state of North Dakota is currently conducting studies related to erionite exposure areas are known to have this vast mountain.

Radiation and Cancer Mesothelioma

Several dozen cases of mesothelioma with radiation therapy for Hodgkin's disease has been found. A 2005 study entitled "Clinical Course of Thoracic Cancers in Hodgkin's Disease Survivors" (P. Das, AK Ng, MA Stevenson, and PM Mauch) exactly establish that patients with Hodgkin's disease who were treated with radiation therapy have a higher risk of disease mesothelioma.
Specifically, this study followed 33 patients with Hodgkin hospitalized Harvard and has grown mesothelioma lung cancer small cell. Of the participating patients, 88 percent had a history of radiotherapy to the thorax as a treatment for their disease. Some patients have suffered from breast cancer in just over a year after being treated for Hodgkin's disease. Whereas other patients contracted Hodgkin mesotheliokma after more than two decades later. Like most patients with mesothelioma, most patients diagnosed with mesothelioma when it reached stage III or IV and the prognosis is very difficult. The survival rate average is only 9 months.
In some cases, peritoneal mesothelioma has also been associated with radiation therapy for breast cancer or other cancers that do to the chest area
Other studies have found a relationship between mesothelioma and thorium dioxide, which is a radioactive substance that is used in conjunction with conventional x-ray to diagnose certain conditions. Thorium dioxide is widely used from the 1920s until the 1950s.
Atomic Radiation and Mesothelioma
In 1995, the first case has been diagnosed with mesothelioma and believed to be associated with the incidence of the atomic bomb on Nagasaki. A report in this case, written by Masami Mizuki, Keiko Yukishige, Yasuharu Abe, and Tomiyasu Tsuda published in the journal Respirology in September 1997. They argue that the combination of exposure to atomic radiation and asbestos (patient worked for 2 years as a shipbuilder in a ammunition factory) was associated with an increased incidence of mesothelioma.
The doctors who wrote the study found, "If the pleural thickening or pleural effusion was found in the atomic bomb survivors, malignant mesothelioma should be considered as an option in the differential diagnosis, even though the atomic bomb attacks several decades ago."
Atomic Energy workers and Mesothelioma
It seems that there is a potential connection to the occurrence of mesothelioma in place with radiation exposure. Over the past few decades, few people currently or previously worked on atomic energy plant have been diagnosed with a rare cancer. In this case thought to be caused by constant exposure to radiation in low levels. (Ionizing radiation: A risk factor for cancer; JE Goodman et al, 2009) It is important to note is the authors concluded that given the low rate of mesothelioma in the general population as well as an increased risk of disease on individuals exposed to radiation, including those working in atomic power plants.
Relationship Between Radiation and Mesothelioma
Knowing about the relationship between radiation and mesothelioma is one of the measures for speeding up diagnosis and saved many people who have been identified as potential victims of mesothelioma. Anyone who has been exposed to radiation in any form, either regularly in the workplace or through x-ray or through therapy for other cancers chest, should always tell their doctor about medical history and history of work despite the radiation exposure occurred a few years earlier. Therefore, if the symptoms include chest pain, shortness of breath, and coughing can be determined relationship with a medical history and a history of the patient work can then be made the correct diagnosis and treatment of mesothelioma begin as soon as possible.

Smoking and Mesothelioma

Telah lama diketahui bahwa merokok berbahaya bagi kesehatan seseorang. Merokok menyebabkan peningkatan tajam dalam kasus kanker paru-paru mesothelioma pada para perokok. Namun perokok yang telah terpapar asbes membawa risiko lebih tinggi terkena penyakit bahkan lebih serius lagi yaitu kanker mesothelioma ganas yang mempengaruhi lapisan paru-paru (mesothelioma pleura), jantung (perikardial mesothelioma ), atau perut (peritoneal mesothelioma) dan sulit untuk diobati.

Paparan asbes telah diidentifikasi sebagai penyebab utama kanker mesothelioma. Penyakit ini terjadi ketika seseorang menghirup serat asbes yang tajam lalu kemudian bersarang di paru-paru. Merokok menurut Centers for Disease Control dapat melemahkan paru-paru dan menurunkan kemampuan tubuh untuk menghilangkan serat asbes. Selanjutnya, asap rokok mengiritasi saluran udara dan menyebabkan mereka untuk menghasilkan lebih banyak lendir yang pada gilirannya memblokir saluran udara dalam menghilangkan serat.

Menurut berbagai studi yang telah dilakukan sepanjang dua dekade terakhir, sementara ini merokok saja tidak menyebabkan mesothelioma. Para perokok yang terpapar asbes berisiko sekitar 50 sampai 84 kali lebih mungkin mengembangkan kanker paru-paru asbes. Dan para ahli sepakat berpendapat bahwa perokok setidaknya dua kali lebih mungkin untuk mengembangkan mesothelioma dalam tubuhnya.

Faktor risiko mesothelioma lebih tinggi bagi mereka yang telah mengidap penyakit Asbestosis yang belum parah yaitu penyakit yang terkait dengan asbestos namun masih bisa ditangani. Dengan merokok satu bungkus sehari bagi penderita asbestosis maka semakin tinggi kesempatan berkembangnya kanker agresif. Oleh karena itu mereka yang telah menderita Asbestosis harus berhenti merokok. Menurut studi yang dilakukan oleh National Cancer Institute menyatakan bahwa berhenti merokok dapat menurunkan sampai 50 persen risiko didiagnosis mesothelioma dalam waktu sekitar lima tahun sejak berhenti merokok. Angka yang menggembirakan bagi perokok dengan penyakit asbes dini.

Perokok yang telah terpapar asbes dan belum berhenti merokok, harus mau melakukan pemeriksaan kesehatan rutin untuk menentukan kesehatan paru-paru mereka. Tes untuk memantau pembentukan kanker asbes mesothelioma misalnya seperti x-ray dada atau tes fungsi paru-paru. Selain itu, mungkin juga diperlukan tes darah sederhana yang dikenal sebagai uji ®Mesomark kepada para perokok yang menderita paparan asbes untuk mendeteksi keberadaan mesothelioma.

Particle And Mesothelioma Cancer

More than 700,000 schools and buildings in the United States today contain asbestos insulation as reported by the US Environmental Protection Agency. Exposure to asbestos does not stop there, but asbestos is often found in shipbuilding, manufacturing facilities, railway facilities and construction sites.Blue-collar workers (workers) are at highest risk for developing mesothelioma due to exposure on the job. They usually work at the aluminum plant, oil refineries, chemical plants, mines, factories, shipyards, construction sites and railway tracks.Employees in closed rooms with air masks facilities are still very vulnerable to exposure. Risk jobs most affected are miners, factory workers, railroad workers, shipbuilding and construction workers - especially those who install equipment containing asbestos insulation. Sometimes the worker's family members also receive residual exposure to asbestos dust and fibers brought home on workers' clothes and also the risk of contracting mesothelioma.There are six types of asbestos: chrysotile, amosite, crocidolite, tremolite, anthophyllite and actinolite. Six types of minerals are divided into two classifications, namely serpentine and amphibole. Chrysotile is the only serpentine mineral classification. As known carcinogens are two classes of asbestos can cause mesothelioma.Chrysotile asbestos is the mineral most commonly used in the United States and is known for his curly fibers that can easily be woven into the fabric. Applications chrysotile including drywall compound, plaster, tile flooring vinyil, roofing materials, ceiling acoustical, fireproofing (flame retardant), putty materials, brake pads and shoes, stage curtains, comforters and cast coating teeth.Amosite and crocidolite asbestos minerals other is more commonly used, although their application is not as extensive as chrysotile. Products derived from minerals include asbestos insulation board, ceiling tiles and casings for water service.In the last ten years, the search asbestos has been found in the powder and the main ingredient of crayons.Exposure and Health RiskThe widespread use of asbestos in various industries not only a risk of people working in the manufacture of asbestos-based products only. But those who might use raw materials of asbestos in everyday life they are also exposed to the carcinogen. Asbestos material attached to the clothes, hair, skin which then contaminate others and the environment.Although chrysotile is the most common form of asbestos used in the product and is a carcinogen. And it is known amosite and crocidolite asbestos are most harmful to health. All types of asbestos can last long to settle in a person's lungs for many years after exposure to asbestos, but the type of amosite and crocidolite are the most persistent particles in the lungs.Higher risk can occur in a worker in an environment associated with asbestos, nevertheless work with minimal exposure can also potentially undergo mesothelioma cancer or other diseases.Although exposure to asbestos may have peaked at the turn of the twentieth century until the 1970s, many people are still being subjected to asbestos particles. Still in debate that the latest mass exposure and tragic is the result of the 9/11 WTC attacks, in which tons of asbestos particles released into the air and endanger thousands of rescue workers and people living near Ground Zero. Many firefighters, police and rescue workers were diagnosed with asbestos cancer that is still battling cancer, continues today.Furthermore, many people continue to be exposed to asbestos in the homes of old buildings that handle the renovation themselves without knowing the potential health risks. Renovating buildings in this neighborhood can be spread asbestos into the air and inhaled into the body.Without knowledge of where asbestos may be present in the physical building of the house, then there is a greater risk for exposure to asbestos as a result of the dismantling of the renovation is done. Therefore, there must be a professional contractor personnel who checked thoroughly before physically building renovation project began. The execution of the destruction of the building should always be handled by professional contractors and recommended not to be done alone.One of the groups hardest hit from asbestos-related diseases are America's veterans. All branches of the US military use of tools, equipment and products with asbestos fibers. It unwittingly expose young men and women between the 1940s and 1970s. Most veterans are repeatedly exposed to asbestos then suffer from mesothelioma.For over a hundred years, almost every product that we hold may have been manufactured with asbestos components. Of goods household ornaments, products manufactured to protect firefighters, for dental products. Asbestos has been a silent killer in American industry.Some research points to get the fact that asbestos fibers have been inhaled more can cause physical irritation resulting in mesothelioma than cancer caused by a chemical reaction naturally. As a fiber that has been inhaled through the mouth and nose they are cleared from the body by way through the mucus in the nose, throat and airways when coughing or vomiting. Amphibole fibers (long and thin) can not be easily removed and therefore the carcinogenic substances left behind and embedded into the lining of the chest, lungs or stomach which causes scarring and inflammation that increases the risk of mesothelioma cancer. Symptoms of mesothelioma can be detected fastest ten years after exposure and can incubate for forty years.Asbestosis (scarring of the lungs) or mesothelioma lung cancer can also be caused by inhalation of asbestos fibers. Even people who were exposed to asbestos can be seven times greater risk of developing lung cancer than others. Workers who are in a high level of asbestos exposure more likely to die from cancer asbestosis, lung or mesothelioma than die from other diseases. It is also believed that inhaling and swallowing asbestos could contribute to the formation of mesothelioma in the abdomen called peritoneal mesothelioma. This disease has also been found in other organs such as the pancreas, larynx and colon. But fewer in number compared with the incidence of lung cancer.Chance of developing mesothelioma was comparable in direct proportion to the duration and amount of asbestos exposure experienced by a person. They were exposed to high levels of asbestos exposure at a young age for a long period of time have a greater risk than those diagnosed with mesothelioma were exposed to asbestos and the low level in the short term.Another important point is that the latency period of mesothelioma is very long. Often 2 to 40 after exposure to asbestos to be diagnosed with mesothelioma. Genetic factors may also play a role which explains why not everyone exposed to asbestos develop asbestos-related diseases.

Mesothelioma Cancer

Mesothelioma is an aggressive cancer affecting the membrane lining of the lungs and abdomen.

Malignant Mesothelioma is the most serious of all asbestos-related diseases. Exposure to asbestos is the primary cause  and risk factor for mesothelioma.

Making a correct mesothelioma diagnosis is particularly difficult for doctors because the disease often presents with symptoms that mimic other common ailments. There is currently no known cure for mesothelioma, but treatments such as surgery and chemotherapy can help to improve the typical mesothelioma prognosis and even increase one's life expectancy.

Three major types of mesothelioma exist and they are differentiated by the organs primarily affected. Pleural mesothelioma (affecting the lung’s protective lining in the chest cavity) represents about three-quarters of all mesothelioma incidence. Peritoneal mesothelioma, which affects the abdominal cavity, and pericardial mesothelioma, which affects the cardiac cavity, comprise the remainder.

 

There are three recognized mesothelioma cell types. Between 50% and 70% of all mesotheliomas are of the  epithelial variety. While prognosis is generally poor, it is considered less aggressive than sarcomatoid mesothelioma and biphasic mesothelioma, which comprise the remainder of cell-type diagnoses.

The cavities within the body encompassing the chest, abdomen, and heart are surrounded by a membrane of cells known as the mesothelium. Mesothelial cells assist in general organ functions. The mesothelium is particularly important to organs that are commonly in motion, such as expansion or contraction of the lungs, stomach, or heart. Lubrication from the mesothelial cells allows free range of motion within the body. The mesothelium of the chest, abdomen, and cardiac cavity are called the pleura, the peritoneum, and the pericardium, respectively. Each of these groupings of mesothelial cells is extremely critical to the functions of the body structures which they encompass.

Malignancies (cancerous tumors) occurring within the mesothelial membranes are known as malignant mesothelioma, or simply mesothelioma. Benign tumors of the mesothelium are known to occur, but are much more rare than malignant mesothelial tumors.

While tumors of the mesothelium were first recognized in the late 18th century, it was not until the middle of the 20th century that this particular cancer was studied and examined with more detail. It was at this time when suspicions of the cancer’s causal relationship with asbestos exposure became more substantiated. A joint reserch venture through the Department of Thoracic Surgery at the University of the Witswater and Johannesburg General Hospital in South Africa provided the most compelling evidence of the nexus between asbestos exposure and the development of pleural mesothelioma.

Incidence of mesothelioma is still quite rare, with only 2,500-3,000 diagnoses in the United States each year. There was a spike in reported diagnoses between 1970 and 1984, which has been attributed to the latency period between diagnosis and the height of industrial exposures, which occurred roughly 40-60 years prior to this time. While exposure was common across the United states in nearly all industries, it was particularly prevalent in the WWII-era military industrial cycle, including navy shipyard.

Although this cancer is much more common in men over the age of 60, mesothelioma in women and children has been documented as well. Mesothelioma causes for diagnosis in women and children are mainly attributed to secondary exposure to asbestos, as it was not uncommon for men to bring asbestos back into the home on their bodies or clothing.